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C8orf70 Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The C8orf70 gene product has been provisionally designated C8orf70 pending further characterization.

Synonyms

C8orf70; Chromosome 8 open reading frame 70; F164A_HUMAN; fam164a; family with sequence similarity 164, member A; Hypothetical protein C8orf70; hypothetical protein LOC51101; Protein FAM164A; CGI 62; CGI-62.

Gene ID

4879

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

101-200/325

Target

CGI62/C8orf70

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human C8orf70

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

4879

Predicted Cross Reactivity

Rat, Dog, Cow, Pig, Horse, Rabbit

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