Tropomyosin Polyclonal Antibody
Product Specifications
Background
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Synonyms
TPM1; Tropomyosin alpha-1 chain; Alpha-tropomyosin; Tropomyosin-1; C15orf13; TMSA; TPM2; Tropomyosin beta chain; Beta-tropomyosin; Tropomyosin-2; TMSB; TPM3; Tropomyosin alpha-3 chain; Gamma-tropomyosin; Tropomyosin-3; TPM4; Tropomyosin alpha-4 chain; TM30p1; Tropomyosin-4
Gene ID
7168
Swiss Prot
P09493
Cellular Locus
Cytoskeleton
Host
Rabbit
Cross Reactivity
Human
Immunogen
201-284/284
Target
Tropomyosin
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human TPM1
Applications
WB, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Specificity
This antibody will detect all 4 Tropomyosin proteins: TPM1, TPM2, TPM3, and TPM4
Gene ID URL
7168
Predicted Cross Reactivity
Mouse, Rat, Dog, Sheep, Zebrafish
Curated Selection
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