Gamma crystallin S Polyclonal Antibody
Product Specifications
Background
Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated , _ and _. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. _S-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. _S-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. _S-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.
Synonyms
Rncat; AI327013; Beta-crystallin S; CRBS_HUMAN; CRYG8; crygs; Crystallin, gamma 8; Crystallin, gamma polypeptide 8; Crystallin, gamma S; Gamma crystallin S; Gamma S crystallin; Gamma-crystallin S; Gamma-S-crystallin; recessive nuclear cataract; Opj.
Host
Rabbit
Cross Reactivity
Rat
Immunogen
121-168/178
Target
Gamma crystallin S
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human gamma crystallin S
Applications
WB, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Pig, Rabbit
Curated Selection
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