TSPEAR Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.
Synonyms
C21orf14; C21orf38; C21orf7; Chromosome 21 open reading frame 38; Chromosome 21 open reading frame 91; Early undferentiated retina and lens; EURL; Protein EURL homolog; YG81; TSEAR_HUMAN.
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
581-669/669
Target
TSPEAR
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human TSPEAR/C21orf9
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IF (IF=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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