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TSPEAR Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.

Synonyms

C21orf14; C21orf38; C21orf7; Chromosome 21 open reading frame 38; Chromosome 21 open reading frame 91; Early undferentiated retina and lens; EURL; Protein EURL homolog; YG81; TSEAR_HUMAN.

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

581-669/669

Target

TSPEAR

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human TSPEAR/C21orf9

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IF (IF=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

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