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AMPD3 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

AMP deaminase plays a critical role in energy metabolism.Involvement in diseaseDefects in AMPD3 are the cause of adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE) ; also known as erythrocyte AMP deaminase deficiency. AMPDDE is a metabolic disorder due to lack of activity of the erythrocyte isoform of AMP deaminase. It is a clinically asymptomatic condition characterized by a 50% increase in steady-state levels of ATP in affected cells. Individuals with complete deficiency of erythrocyte AMP deaminase are healthy and have no hematologic disorders.

Synonyms

Adenosine monophosphate deaminase isoform E; Adenosine monophosphate deaminase 3; AMP aminohydrolase; AMP deaminase 3; AMP deaminase isoform E; Ampd3; AMPD3_HUMAN; Erythrocyte AMP deaminase; Erythrocyte specic AMP deaminase; Erythrocyte type AMP deaminase; Myoadenylate deaminase.

Gene ID

272

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

21-120/767

Target

AMPD3

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human AMPD3

Applications

IF

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

IF (IF=1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

272

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