DL-dithiothreitol
DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond[1][2].
Product Specifications
CAS Number
[3483-12-3]
Product Name Alternative
DTT; rel- (2R,3R) -1,4-Dimercapto-2,3-butanediol
UNSPSC
12352200
Hazard Statement
H302, H315, H318, H402
Target
Biochemical Assay Reagents; Disulfidptosis
Type
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/DTT.html
Concentration
10mM
Purity
99.8
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
SC[C@@H](O)[C@H](O)CS
Molecular Formula
C4H10O2S2
Molecular Weight
154.25
Precautions
H302, H315, H318, H402
References & Citations
[1]Dithiothreitol, From Wikipedia|[2]Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24 (1) : 183.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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