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PKM1 Recombinant Rabbit Monoclonal Antibody [PSH04-37]

Pyruvate kinase isozymes M1/M2 (PKM1/M2), also known as pyruvate kinase muscle isozyme (PKM), pyruvate kinase type K, cytosolic thyroid hormone-binding protein (CTHBP), thyroid hormone-binding protein 1 (THBP1), or opa-interacting protein 3 (OIP3), is an enzyme that in humans is encoded by the PKM2 gene. Two isozymes are encoded by the PKM gene: PKM1 and PKM2. The M-gene consists of 12 exons and 11 introns. PKM1 and PKM2 are different splicing products of the M-gene (exon 9 for PKM1 and exon 10 for PKM2) and solely differ in 23 amino acids within a 56-amino acid stretch (aa 378–434) at their carboxy terminus.

Product Specifications

Product Name Alternative

CTHBP antibody Cytosolic thyroid hormone-binding protein antibody KPYM_HUMAN antibody OIP-3 antibody Opa-interacting protein 3 antibody p58 antibody pkm antibody PKM1 antibody PKM2 antibody Pyruvate kinase 2/3 antibody Pyruvate kinase muscle isozyme antibody Pyruvate kinase PKM antibody THBP1 antibody Thyroid hormone-binding protein 1 antibody Tumor M2-PK antibody

Abbreviation

M1-PK, PKM1

Swiss Prot

P14618-2 Human, P52480 Mouse, P11980 Rat

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within human PKM1 aa 389-433 / 531 (P14618-2).

Isotype

IgG

Clone

PSH04-37

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

HCT 116 cell lysate, U-87 MG cell lysate, HeLa cell lysate, human brain tissue lysate, mouse brain tissue lysate, mouse heart tissue lysate, HCT 116, human heart tissue, mouse heart tissue, rat heart tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:500 ;IHC-P: 1:5,000-1:30,000 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 58 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

CAS Number

9000-83-3

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