5 MethylCytosine Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs) to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.
Synonyms
5-Methyl Cytidine; 5 m C; 5 mC; 5 me C; 5 Me Cytidine; 5 MeCyd; 5 Methyl Cytidine; 5 MethylCytosine; 5-mC; 5-Me Cytidine; 5-Methyl-Cytosine; 5-MethylCytidine.
Host
Rabbit
Cross Reactivity
Human, Others
Target
5 MethylCytosine
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated 5 MethylCytosine
Applications
WB, FCM, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Cross Reactivity Details
5 MethylCytosine
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6278045-01 0.2 mL
BCL9L, NT (BCL9L, DLNB11, B Cell CLL/lymphoma 9-like protein, Protein BCL9-2) (Biotin)
Ask
View Details MBS6278045-02 5x 0.2 mL
BCL9L, NT (BCL9L, DLNB11, B Cell CLL/lymphoma 9-like protein, Protein BCL9-2) (Biotin)
Ask
View Details 
MBS6036407-01 10 mg
Phenylethynsulfonic Acid Amide (Phenyl-ethynesulfonic Acid Amide, Pifithrin-u, PFTu)
Ask
View Details MBS6036407-02 5x 10 mg
Phenylethynsulfonic Acid Amide (Phenyl-ethynesulfonic Acid Amide, Pifithrin-u, PFTu)
Ask
View Details