KChIP2 Polyclonal Antibody
Product Specifications
Background
The downstream regulatory element, DRE, acts as a location-dependent gene silencer. DREAM (for DRE-antagonist modulator) is a Ca2+-regulated transcriptional repressor that specifically binds to the DRE. DREAM regulates transcription of prodynorphin and c-Fos genes and shows 99% nucleotide homology to the Kv channel-interacting proteins (KChIPs) . KChIP family members include KChIP1, which is expressed in brain, KChIP2, which is expressed in heart, brain, and lung, KChIP3 (also designated calsenilin), which is expressed in brain and testis and KChIP4.
Synonyms
KCNIP-2; A type potassium channel modulatory protein 2; A-type potassium channel modulatory protein 2; Cardiac voltage gated potassium channel modulatory subunit; Cardiac voltage-gated potassium channel modulatory subunit; DKFZp566L1246; KChIP 2; KChIP2; KCIP2_HUMAN; KCNIP 2; Kcnip2; Kv channel interacting protein 2; Kv channel-interacting protein 2; MGC17241; Potassium channel interacting protein 2; Potassium channel-interacting protein 2.
Gene ID
30819
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
1-100/270
Target
KChIP2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human KChIP2
Applications
WB, ELISA, IHC-P, IHC-F, IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), ELISA (ELISA=1:5000-10000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500), IF (IF=1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
30819
Curated Selection
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