TSPAN16 Polyclonal Antibody
Product Specifications
Background
TM4-B, also known as TSPAN16 (tetraspanin-16) or TM4SF16 (transmembrane 4 superfamily member 16), is a 245 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the TM4SF family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4-B is broadly expressed in most human tissues and cell lines including neural and bone marrow derived tissues. The gene that encodes TM4-B contains nearly 31,000 bases and maps to human chromosome 19p13.2. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs) .
Synonyms
TM-8; TM4-B; TM4SF16; Tetraspanin-16; Tspan-16; Tetraspanin TM4-B; Transmembrane 4 superfamily member 16; TSPAN16
Gene ID
26526
Swiss Prot
Q9UKR8
Cellular Locus
Extracellular
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
81-93/245
Target
TSPAN16
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human TSPAN16/TM4-B
Applications
WB, FCM, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
26526
Predicted Cross Reactivity
Human
Curated Selection
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