Sp-8-Br-cAMPS
Sp-8-Br-cAMPS is an analog of cAMP. Sp-8-Br-cAMPS is an agonist for cAMP, which performs a protein kinase A (PKA) activating activity with EC50 of 360 nM. Sp-8-Br-cAMPS inhibits proliferation of T cells and the haemocyte non-self response in Lepidoptera larve[1][2].
Product Specifications
CAS Number
127634-20-2
UNSPSC
12352005
Target
PKA
Type
Reference compound
Related Pathways
Stem Cell/Wnt; TGF-beta/Smad
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sp-8-br-camps.html
Smiles
NC1=NC=NC2=C1N=C(Br)N2[C@H]3[C@H](O)[C@H](O4)[C@@H](CO[P@@]4(S)=O)O3
Molecular Formula
C10H11BrN5O5PS
Molecular Weight
424.17
References & Citations
[1]Aandahl EM, et al., Inhibition of antigen-specific T cell proliferation and cytokine production by protein kinase A type I. J Immunol. 2002 Jul 15;169 (2) :802-8.|[2]Brooks CL, et al., Protein kinase A affects Galleria mellonella (Insecta: Lepidoptera) larval haemocyte non-self responses. Immunol Cell Biol. 2005 Apr;83 (2) :150-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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