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MARCH4 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Synonyms

E3 ubiquitin protein ligase MARCH4; RNF174; KIAA1399; MARCH 4; MARCH IV; Membrane associated RING CH protein IV; Membrane associated ring finger C3HC4 4; Membrane associated RING finger protein 4; mKIAA1399; RING finger protein 174; MARH4_HUMAN.

Gene ID

57574

Host

Rabbit

Cross Reactivity

Human

Immunogen

261-360/410

Target

MARCH4

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human MARCH4

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

57574

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

Curated Selection

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