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LRCH3 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Members of the leucine-rich repeat family includes LRCH1, LRCH2, LRCH3 and LRCH4. All family members contain one calponin-homology domain and nine leucine-rich repeats. The best characterized leucine-rich repeat family member is LRCH4, which is suggested to be involved in ligand binding in the brain, with expression observed primarily in the hippocampus. As a cell adhesion molecule and signal receptor, LRCH4 may play an important role in maintenance of hippocampus-dependent memories, with defects in the gene possibly contributing to a loss of long-term memory. The gene encoding LRCH3 maps to human chromosome 3, which spans 200 million base pairs and encodes between 1,100 and 1,500 genes. There are three isoforms of LRCH3 that are produced as a result of alternative splicing events.

Synonyms

Leucine rich repeats and calponin homology CH domain containing 3; LRCH3; MGC4126; LRCH3_HUMAN.

Gene ID

84859

Host

Rabbit

Cross Reactivity

Rat

Immunogen

301-400/777

Target

LRCH3

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human LRCH3

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

84859

Predicted Cross Reactivity

Human, Mouse, Dog, Cow, Sheep, Horse, Chicken, Rabbit

Curated Selection

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