Mecbotamab vedotin
Mecbotamab vedotin (BA3011) is a pH dependent antibody drug conjugate (ADC) targeting AXL. Mecbotamab vedotin can significantly inhibit AXL in DU145 cells and LCLC-103H cells and kills cells. Mecbotamab vedotin can be used for research on cancer such as lung cancer, pancreatic cancer and prostate cancer. The antibody component is Mecbotamab , and the ADC toxin molecule is Vedotin (HY-15162).
Product Specifications
CAS Number
2460400-64-8
Product Name Alternative
BA3011; CAB-Axl-ADC; CAB-anti-Axl-ADC
UNSPSC
12352100
Target
Antibody-Drug Conjugates (ADCs) ; TAM Receptor
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mecbotamab-vedotin.html
Purity
99.11
Solubility
10 mM in DMSO
Smiles
[Mecbotamabvedotin]
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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