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ARHGAP32 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity) .

Synonyms

GRIT; RICS; GC-GAP; PX-RICS; p250GAP; p200RhoGAP; Rho GTPase-activating protein 32; Brain-specific Rho GTPase-activating protein; GAB-associated Cdc42/Rac GTPase-activating protein; GTPase regulator interacting with TrkA; Rho-type GTPase-activating protein 32; Rho/Cdc42/Rac GTPase-activating protein RICS; RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling; ARHGAP32; KIAA0712

Gene ID

9743

Swiss Prot

A7KAX9

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

801-920/2078

Target

ARHGAP32

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human ARHGAP32

Applications

IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

9743

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