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C1orf187/Draxin Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.

Synonyms

AGPA3119; C1orf187; Chromosome 1 open reading frame 187; Dorsal repulsive axon guidance protein; DRAXI_HUMAN; Draxin; Neucrin; UNQ3119.

Gene ID

374946

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

261-349/349

Target

C1orf187/Draxin

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human C1orf187

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

374946

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