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SERPINB3 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. SCCA2 may act as a protease inhibitor to modulate the host immune response against tumor cells.

Synonyms

HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine or cysteine proteinase inhibitor clade B ovalbumin member 3; Serpin B3; Serpin peptidase inhibitor clade B ovalbumin member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A; SCCA 2; SCCA2; Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor leucine serpin; SCCA-2; SCCA1; SCCA2/SCCA1 fusion protein; Serine or cysteine proteinase inhibitor, clade B ovalbumin, member 4; Serpin B4; Serpin peptidase inhibitor, clade B ovalbumin, member 4; SERPINB 4; SERPINB4; SPB4_HUMAN; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2.

Gene ID

6317

Host

Rabbit

Cross Reactivity

Human

Immunogen

71-170/390

Target

SERPINB3

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human SERPINB3 (same as SERPINB4)

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF ()

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6317

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