SERPINB3 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. SCCA2 may act as a protease inhibitor to modulate the host immune response against tumor cells.

HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine or cysteine proteinase inhibitor clade B ovalbumin member 3; Serpin B3; Serpin peptidase inhibitor clade B ovalbumin member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A; SCCA 2; SCCA2; Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor leucine serpin; SCCA-2; SCCA1; SCCA2/SCCA1 fusion protein; Serine or cysteine proteinase inhibitor, clade B ovalbumin, member 4; Serpin B4; Serpin peptidase inhibitor, clade B ovalbumin, member 4; SERPINB 4; SERPINB4; SPB4_HUMAN; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2.