SERPINB3 Polyclonal Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. SCCA2 may act as a protease inhibitor to modulate the host immune response against tumor cells.
Synonyms
HsT1196; Protein T4 A; Protein T4-A; SCC; SCCA PD; SCCA-1; SCCA1; SCCAPD; Serine or cysteine proteinase inhibitor clade B ovalbumin member 3; Serpin B3; Serpin peptidase inhibitor clade B ovalbumin member 3; SERPINB3; SPB3_HUMAN; Squamous cell carcinoma antigen 1; T4 A; T4A; SCCA 2; SCCA2; Leupin; Peptidase inhibitor 11; PI 11; PI-11; PI11; Protease inhibitor leucine serpin; SCCA-2; SCCA1; SCCA2/SCCA1 fusion protein; Serine or cysteine proteinase inhibitor, clade B ovalbumin, member 4; Serpin B4; Serpin peptidase inhibitor, clade B ovalbumin, member 4; SERPINB 4; SERPINB4; SPB4_HUMAN; Squamous cell carcinoma antigen 1; Squamous cell carcinoma antigen 2.
Gene ID
6317
Host
Rabbit
Cross Reactivity
Human
Immunogen
71-170/390
Target
SERPINB3
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human SERPINB3 (same as SERPINB4)
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
6317
Curated Selection
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