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BAGE4 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Product Specifications

Background

Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements. BAGE, also known as B melanoma antigen 1 or cancer/testis antigen 2.1, is a 43 amino acid member of the BAGE family. Generally, BAGE proteins are not expressed in normal tissues, except in testis, but are expressed highly in melanomas, bladder carcinomas, head and neck squamous cell carcinomas, and lung and breast cancer carcinomas. BAGE proteins are not expressed in renal, colorectal and prostatic carcinomas, leukemias and lymphomas.

Synonyms

B melanoma antigen 4; B melanoma antigen family, member 4; BAGE4; BAGE4_HUMAN; Cancer/testis antigen 2.4; CT2.4; MGC119851; MGC119852; MGC119853; MLL3P.

Gene ID

3624

Host

Rabbit

Cross Reactivity

Human

Immunogen

18-39/39

Target

BAGE4

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 350

Source

KLH conjugated synthetic peptide derived from human BAGE4

Applications

IF

Purification

Purified by Protein A.

Excitation Emission

346nm/442nm

Concentration

1µg/µl

Dilution

IF (IF=1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3624

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