ATAD2 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.
Synonyms
ANCCA; CT137; PRO2000; ATPase family AAA domain-containing protein 2; AAA nuclear coregulator cancer-associated protein; ATAD2; L16
Gene ID
29028
Swiss Prot
Q6PL18
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
1001-1300/1390
Target
ATAD2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human ATAD2
Applications
IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
29028
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