ANKS1B Polyclonal Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
The _-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer?s disease patients and AbPP intracellular domain (AID) . AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.
Synonyms
AIDA 1; AIDA-1; Amyloid-beta protein intracellular domain-associated protein 1; Anks1b; Ankyrin repeat and sterile alpha mot domain-containing protein 1B; ANS1B_HUMAN; E2A-PBX1-associated protein; EB-1.
Gene ID
56899
Swiss Prot
Q7Z6G8
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
851-1000/1248
Target
ANKS1B
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic peptide derived from human ANKS1B/AIDA1
Applications
IF
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1µg/µl
Dilution
IF (IF=1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
56899
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