Phospho-Dishevelled 2 (Thr224) Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity) .

Synonyms

Segment polarity protein dishevelled homolog DVL-2; Dishevelled-2; DSH homolog 2; DVL2

Gene ID

1856

Swiss Prot

O14641

Modification Site

Thr224

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

Phospho-Dishevelled 2 (Thr224)

Clonality

Polyclonal

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This antibody will recognize DVL3 when phosphorylated at Thr205

Gene ID URL

1856

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TT-DT-16 1 Unit

Block for 96-well Sample Concentrator TT-200-96SC, 96x0.2ml PCR plate

Ask

View Details

A25141-50UL 50 μL

HIST1H4A (Ab-8) Antibody

Ask

View Details

SR318828 1 Kit

TPTE2P1 Human siRNA Oligo Duplex (Locus ID 646405)

Ask

View Details

223359-01 50 µL

Hox-B9 (Homeobox Protein Hox-B9, Homeobox Protein Hox-2.5, Homeobox Protein Hox-2E, HOXB9, HOX2E) discontinued

Ask

View Details

223359-02 100 µL

Hox-B9 (Homeobox Protein Hox-B9, Homeobox Protein Hox-2.5, Homeobox Protein Hox-2E, HOXB9, HOX2E) discontinued

Ask

View Details

RN203202 10 µg

Rasl11b (NM_001002830) Rat Untagged Clone

Ask

View Details