Phospho-Dishevelled 2 (Thr224) Polyclonal Antibody, PE-Cy5.5 Conjugated
Product Specifications
Background
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity) .
Synonyms
Segment polarity protein dishevelled homolog DVL-2; Dishevelled-2; DSH homolog 2; DVL2
Gene ID
1856
Swiss Prot
O14641
Modification Site
Thr224
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Dishevelled 2 (Thr224)
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5.5
Source
KLH conjugated synthetic phosphopeptide derived from human DVL2 around the phosphorylation site of Thr224
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This antibody will recognize DVL3 when phosphorylated at Thr205
Gene ID URL
1856
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
