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DPCR1 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

Synonyms

Dfuse panbronchiolitis critical region 1; Dfuse panbronchiolitis critical region; Dfuse panbronchiolitis critical region protein 1; DKFZp666O235; DPCR protein; MGC126710; MGC126712; OTTHUMP00000062447; PBLT; bCX105N19.6; DPCR1_HUMAN.

Gene ID

135656

Cellular Locus

Extracellular

Host

Rabbit

Cross Reactivity

Human

Immunogen

121-220/517

Target

DPCR1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human DPCR1

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

135656

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