TRPM7 Polyclonal Antibody, Cy7 Conjugated
Product Specifications
Background
Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1) .
Synonyms
CHAK; CHAK1; ALSPDC; LTRPC7; LTrpC-7; TRP-PLIK; Transient receptor potential cation channel subfamily M member 7; Channel-kinase 1; Long transient receptor potential channel 7; TRPM7
Gene ID
54822
Swiss Prot
Q96QT4
Cellular Locus
Extracellular
Host
Rabbit
Cross Reactivity
Human
Immunogen
801-900/1865
Target
TRPM7
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy7
Source
KLH conjugated synthetic peptide derived from human TRPM7
Applications
WB, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
743nm/767nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
54822
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
IHUBIDKTC 1 Each
Human BH3 Interacting Domain Death Agonist Chemiluminescent Immunoassay Kit
Sign In for Pricing
View Details 
041071 200 µL
RLN1/RLN2, CT (RLN1, Prorelaxin H1, Relaxin B chain, Relaxin A chain)
Sign In for Pricing
View Details 