PDZD6 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity) . Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779) .
Synonyms
Protein inturned; Inturned planar cell polarity effector homolog; PDZ domain-containing protein 6; INTU; KIAA1284; PDZD6; PDZK6; INTU_HUMAN.
Gene ID
27152
Swiss Prot
Q9ULD6
Cellular Locus
Cytoplasm, Cell membrane, Cytoskeleton
Host
Rabbit
Cross Reactivity
Human
Immunogen
301-400/942
Target
PDZD6
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human PDZD6
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
27152
Predicted Cross Reactivity
Mouse, Rat, Rabbit
Curated Selection
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