ISLR2 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å / horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.
Synonyms
Immunoglobulin superfamily containing leucine-rich repeat protein 2; Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein; ISLR2_HUMAN.
Gene ID
57611
Cellular Locus
Extracellular
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
531-630/745
Target
ISLR2
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human ISLR2
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IF (IF=1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
57611
Curated Selection
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