Transportin 1 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.
Synonyms
Importin 2; Importin beta 2; IPO 2; IPO2; Karyopherin importin beta 2; Karyopherin beta 2; KPN B2; KPNB 2; KPNB2; M9 interacting protein; M9 region interacting protein; M9 region interaction protein; M9-interacting protein; MIP 1; MIP; MIP1; TNPO 1; TNPO1; Transportin 1; Transportin; Transportin-1; Transportin1; TRN; TNPO1_HUMAN.
Gene ID
3842
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
1-100/898
Target
Transportin 1
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human Transportin 1
Applications
WB, IF
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (WB=1:500-2000), IF (IF=1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3842
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