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Transportin 1 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Transportin 1 is the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. In cases of HIV-1 infections, transportin 1 is known to bind and mediate the nuclear import of HIV-1 Rev.

Synonyms

Importin 2; Importin beta 2; IPO 2; IPO2; Karyopherin importin beta 2; Karyopherin beta 2; KPN B2; KPNB 2; KPNB2; M9 interacting protein; M9 region interacting protein; M9 region interaction protein; M9-interacting protein; MIP 1; MIP; MIP1; TNPO 1; TNPO1; Transportin 1; Transportin; Transportin-1; Transportin1; TRN; TNPO1_HUMAN.

Gene ID

3842

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

1-100/898

Target

Transportin 1

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human Transportin 1

Applications

WB, IF

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IF (IF=1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3842

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