IP3 Receptor Polyclonal Antibody
Product Specifications
Background
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity) .
Synonyms
ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor; ITPR1
Gene ID
3708
Swiss Prot
Q14643
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
101-200/2758
Target
IP3 Receptor
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human IP3 Receptor
Applications
Flow-Cyt, ICC/IF
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
Flow-Cyt (Flow-Cyt=2ug/Test), ICC/IF (ICC/IF=1:100)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
3708
Available Sizes
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