HMG4/HMGB3 Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]) .[supplied by OMIM, Mar 2008] Function : Binds preferentially single-stranded DNA and unwinds double stranded DNA. Similarity : Belongs to the HMGB family. Contains 2 HMG box DNA-binding domains.
Synonyms
High mobility group (nonhistone chromosomal) protein 4; High mobility group box 3; High mobility group protein 2a; High mobility group protein 4; High mobility group protein B3; High mobility group protein HMG4; HMG 4; HMG-2a; HMG-4; HMG2A; HMGB 3; HMGB3; HMGB3_HUMAN; MGC90319; Non histone chromosomal protein; Nonhistone chromosomal protein HMG4.
Gene ID
3149
Swiss Prot
O15347
Cellular Locus
Cytoplasm, Nucleus, Chromosome
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
1-100/200
Target
HMG4/HMGB3
Clonality
Polyclonal
Isotype
IgG
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human HMG4/HMGB3:1-100/200
Applications
IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3149
Curated Selection
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