LRP130/LRPPRC Polyclonal Antibody, PerCP Conjugated

Product Specifications

Background

Leucine-rich protein (LRP130) is a cytoplasmic mRNA-binding protein likely to be involved in the processing of mitochondrial DNA transcripts. Defects in the LRPPRC gene that encodes LRP130 result in the French-Canadian type of Leigh syndrome, a severe neurological disorder characterized by lesions in the subcortical region of the brain. LRP130 also interacts with the low-affinity receptor for leukemia inhibitory factor to produce an intracelluar signal cascade.

Synonyms

LRPPRC; 130 kDa leucine-rich protein; GP130; Leucine-rich PPR-mot containing protein; LRP 130; LPPRC_HUMAN.

Host

Rabbit

Cross Reactivity

Rat

Immunogen

165-270/1394

Target

LRP130/LRPPRC

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human LRP130

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Predicted Cross Reactivity

Human, Mouse, Horse, Chicken, Rabbit

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