LRP130/LRPPRC Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Leucine-rich protein (LRP130) is a cytoplasmic mRNA-binding protein likely to be involved in the processing of mitochondrial DNA transcripts. Defects in the LRPPRC gene that encodes LRP130 result in the French-Canadian type of Leigh syndrome, a severe neurological disorder characterized by lesions in the subcortical region of the brain. LRP130 also interacts with the low-affinity receptor for leukemia inhibitory factor to produce an intracelluar signal cascade.
Synonyms
LRPPRC; 130 kDa leucine-rich protein; GP130; Leucine-rich PPR-mot containing protein; LRP 130; LPPRC_HUMAN.
Host
Rabbit
Cross Reactivity
Rat
Immunogen
165-270/1394
Target
LRP130/LRPPRC
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human LRP130
Applications
WB, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Mouse, Horse, Chicken, Rabbit
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