IRE1 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Synonyms
IRE1; IRE1P; IRE1a; hIRE1p; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; Ire1-alpha; ERN1
Gene ID
2081
Swiss Prot
O75460
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
252-260/977
Target
IRE1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human IRE1a
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-8680R-Biotin
Gene ID URL
2081
Predicted Cross Reactivity
Mouse, Dog, Cow, Pig, Horse, Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1603430-01 48 Well
Porcine Visceral Adipose-specific Serine Protease Inhibitor ELISA Kit
Ask
View Details 
MBS1603430-02 96 Well
Porcine Visceral Adipose-specific Serine Protease Inhibitor ELISA Kit
Ask
View Details MBS1603430-03 5x 96 Well
Porcine Visceral Adipose-specific Serine Protease Inhibitor ELISA Kit
Ask
View Details MBS1603430-04 10x 96 Well
Porcine Visceral Adipose-specific Serine Protease Inhibitor ELISA Kit
Ask
View Details