TESPA1 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity) . Plays a role in T-cell antigen receptor (TCR) -mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release and mitochondrial Ca2+ uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.
Synonyms
Protein TESPA1; TESPA1; Thymocyte-expressed positive selection-associated protein 1; KIAA0748; HSPC257
Gene ID
9840
Swiss Prot
A2RU30
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Immunogen
231-330/521
Target
TESPA1
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human TESPA1
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
9840
Predicted Cross Reactivity
Rabbit
Curated Selection
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