USP22 Polyclonal Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

Synonyms

USP3L; Ubiquitin carboxyl-terminal hydrolase 22; Deubiquitinating enzyme 22; Ubiquitin thioesterase 22; Ubiquitin-specific-processing protease 22; USP22; KIAA1063

Gene ID

23326

Swiss Prot

Q9UPT9

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

121-220/525

Target

USP22

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic peptide derived from human USP22

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

23326

Predicted Cross Reactivity

Mouse, Dog, Cow, Sheep, Horse, Chicken, Rabbit, Xenopuslaevis

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