Hemoglobin Beta Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.

Synonyms

CD113t-C; beta-globin; Hemoglobin subunit beta; Hemoglobin beta chain; HBB; Hemoglobin subunit delta; HBD; Delta-globin; Hemoglobin delta chain

Gene ID

3043; 3045

Swiss Prot

P68871; P02042

Cellular Locus

Cytoplasm, Secreted

Host

Rabbit

Cross Reactivity

Human

Immunogen

51-147/147

Target

Hemoglobin Beta

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human Hemoglobin beta

Applications

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

Antibody has equal affinity for Human Hemoglobin Beta and Delta

Gene ID URL

3043; 3045

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