ZNF537 Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. TSHZ3 (teashirt zinc finger homeobox 3), also known as KIAA1474, TSH3 or ZNF537, is a 1,081 amino acid protein that contains one homeobox DNA-binding domain and five C2H2-type zinc fingers. Localized to the nucleus, TSHZ3 functions as a transcriptional regulator that is involved in developmental processes throughout the body. The gene encoding TSHZ3 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
Synonyms
Teashirt homolog 3; Zinc finger protein 537; TSHZ3; TSH3; ZNF537; TSH3_HUMAN.
Gene ID
57616
Cellular Locus
Nucleus
Host
Rabbit
Immunogen
461-570/1081
Target
ZNF537
Clonality
Polyclonal
Isotype
IgG
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human TSHZ3/ZNF537
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
57616
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Pig, Horse, Chicken, Rabbit
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