STIM1 Polyclonal Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

Plays a role in mediating store-operated Ca (2+) entry (SOCE), a Ca (2+) influx following depletion of intracellular Ca (2+) stores. Acts as Ca (2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca (2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca (2+) release-activated Ca (2+) (CRAC) channel subunit, TMEM142A/ORAI1.

Synonyms

GOK; TAM; TAM1; IMD10; STRMK; D11S4896E; Stromal interaction molecule 1; STIM1

Gene ID

6786

Swiss Prot

Q13586

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

85-180/685

Target

STIM1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human STIM1

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

May cross react with STIM2

Gene ID URL

6786

Predicted Cross Reactivity

Human, Mouse, Dog, Cow, Pig, Horse, Chicken, Rabbit

Curated Selection

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