FBXL3 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein) -type E3 ubiquitin ligase complex involved in circadian clock function. The SCF (FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Synonyms
F box and leucine rich repeat protein 3; F box and leucine rich repeat protein 3A; F box protein Fbl3a; F-box and leucine-rich repeat protein 3A; F-box/LRR-repeat protein 3; F-box/LRR-repeat protein 3A; FBL3; FBL3A; Fbxl3; FBXL3_HUMAN; FBXL3A.
Gene ID
26224
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Immunogen
151-250/428
Target
FBXL3
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human FBXL3
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
26224
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Sheep, Pig, Horse, Rabbit
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