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Phospho-GluR1 (Ser836) Polyclonal Antibody, HRP Conjugated

Product Specifications

Background

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Synonyms

Glutamate Receptor 1 phospho S836; Glutamate Receptor 1 phospho Ser836; p-GluR1Ser836; p-GluR1r836; GLUR 1; GLUR A; AMPA 1; AMPA selective glutamate receptor 1; GLUH 1; GLUH1; GluR K1; GluR-1; GluR-A; GluR-K1; GLUR1; GLURA ; GluRK1; Glutamate receptor 1; Glutamate receptor ionotropic AMPA 1; Gria 1; Gria1; Gria1; HBGR1; MGC133252; GRIA1_HUMAN.

Gene ID

2890

Modification Site

Ser836

Cellular Locus

Cytoplasm, Cell membrane, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human

Target

Phospho-GluR1 (Ser836)

Clonality

Polyclonal

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic phosphopeptide derived from human GluR1 around the phosphorylation site of Ser836

Applications

ELISA

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2890

Predicted Cross Reactivity

Mouse, Rat

Curated Selection

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