BXDC2 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
BXDC2 is a 306 amino acid protein encoded by the human gene BXDC2. BXDC2 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region that is homologous to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1) . Pitx1 is part of a complex that includes BXDC5, BXDC1 and PPAN. This complex is required for the biogenesis of the 60S ribosomal subunit. BXDC2 exhibits the same functions as Pitx1.
Synonyms
BRIX; Brix domain containing 2; Brix domain containing protein 2; BRIX1; BRX1, biogenesis of ribosomes, homolog S. cerevisiae; FLJ11100; Ribosome biogenesis protein Brix; BRX1_HUMAN.
Gene ID
55299
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
51-150/353
Target
BXDC2
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human BXDC2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
55299
Predicted Cross Reactivity
Mouse, Rat, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Curated Selection
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