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BXDC2 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

BXDC2 is a 306 amino acid protein encoded by the human gene BXDC2. BXDC2 is a nuclear protein that contains one Brix domain. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region that is homologous to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1) . Pitx1 is part of a complex that includes BXDC5, BXDC1 and PPAN. This complex is required for the biogenesis of the 60S ribosomal subunit. BXDC2 exhibits the same functions as Pitx1.

Synonyms

BRIX; Brix domain containing 2; Brix domain containing protein 2; BRIX1; BRX1, biogenesis of ribosomes, homolog S. cerevisiae; FLJ11100; Ribosome biogenesis protein Brix; BRX1_HUMAN.

Gene ID

55299

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

51-150/353

Target

BXDC2

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human BXDC2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

55299

Predicted Cross Reactivity

Mouse, Rat, Cow, Sheep, Pig, Horse, Chicken, Rabbit

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