GLIPR2 Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.
Synonyms
GAPR 1; GAPR-1; GAPR1_HUMAN; GLI pathogenesis related 2; Glioma pathogenesis related protein 2; Glioma pathogenesis-related protein 2; GliPR 2; GLIPR2; Golgi associated plant pathogenesis related protein 1; Golgi associated PR 1 protein; Golgi-associated plant pathogenesis-related protein 1; Golgi-associated PR-1 protein; OTTMUSP00000007558; RP11-421H8.5; RP23-209M8.2; C77180; 5730414A08Rik; C9orf19.
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
51-154/154
Target
GLIPR2
Clonality
Polyclonal
Isotype
IgG
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human GLIPR2
Applications
ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit
Curated Selection
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