RNF160 Polyclonal Antibody, FITC Conjugated
Product Specifications
Background
E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875) . Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity) .
Synonyms
RNF160; ZNF294; C21orf10; C21orf98; E3 ubiquitin-protein ligase listerin; RING finger protein 160; Zinc finger protein 294; LTN1; KIAA0714; HSPC087
Gene ID
26046
Swiss Prot
O94822
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Immunogen
21-120/1766
Target
RNF160
Clonality
Polyclonal
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human RNF160/ZNF294
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
26046
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Sheep, Horse
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