RNF160 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875) . Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity) .

Synonyms

RNF160; ZNF294; C21orf10; C21orf98; E3 ubiquitin-protein ligase listerin; RING finger protein 160; Zinc finger protein 294; LTN1; KIAA0714; HSPC087

Gene ID

26046

Swiss Prot

O94822

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Immunogen

21-120/1766

Target

RNF160

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human RNF160/ZNF294

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

26046

Predicted Cross Reactivity

Human, Mouse, Rat, Cow, Sheep, Horse

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