Ube2G2 Polyclonal Antibody, RBITC Conjugated

UBE2G2 (Ubiquitin-conjugating enzyme E2 G2), also known as UBC7, is a 165 amino acid protein involved in ubiquitin-mediated protein degradation. Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s) . UBE2G2 is an E2 ubiquitin-conjugating enzyme that acts to catalyze the covalent attachment of ubiquitins to various proteins. Expressed throughout the body, UBE2G2 shares 100% sequence identity with its mouse counterpart and is thought to be involved in endoplasmic reticulum-associated degradation (ERAD) . Two isoforms of UBE2G2 exist due to alternative splicing events.

Human ubiquitin conjugating enzyme G29; UB2G2_HUMAN; UBC 7; UBC7; UBC7 homolog yeast; UBE2G2; Ubiquitin carrier protein G2; Ubiquitin conjugating enzyme 7; Ubiquitin conjugating enzyme E2 G2; Ubiquitin conjugating enzyme E2G 2 homologous to yeast UBC7; Ubiquitin conjugating enzyme E2G 2 UBC7 homolog yeast; Ubiquitin conjugating enzyme E2G 2; Ubiquitin conjugating enzyme G2; Ubiquitin protein ligase G2; Ubiquitin-conjugating enzyme E2 G2; Ubiquitin-protein ligase G2.