FGFR1OP2 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated
Product Specifications
Background
FGFR1OP2 belongs to the SIKE family. The FGFR1OP2 (FGFR1 oncogene partner 2) gene was identified through its involvement in a fusion with the FGFR1 gene. FGFR1OP2 may be involved in the wound healing pathway. It is expressed in bone marrow, spleen and thymus. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD) . Insertion ins (12;8) (p11; p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T cell or B cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
Synonyms
DKFZp564O1863; FGFR1 oncogene partner 2; HSPC123; HSPC123 like; FGOP2_HUMAN.
Gene ID
26127
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
51-150/253
Target
FGFR1OP2
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 750
Source
KLH conjugated synthetic peptide derived from human FGFR1OP2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
749nm/775nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
26127
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Horse, Rabbit
Curated Selection
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